41. Meg Ryan, 54 years old
42. Julianne Moore, 55 years old
43. Allison Janney, 56 years old
44. Emma Thompson, 57 years old
45. Ellen DeGeneres, 58 years old
46. Frances McDormand, 59 years old
47. Whoopi Goldberg, 60 years old
48. Laurie Metcalf, 61 years old
49. Oprah Winfrey, 62 years old
50. Mary Steenburgen, 63 years old
51. Christine Baranski, 64 years old
52. Anjelica Huston, 65 years old
Tell us about your favorite actress in the comment section, hope the age difference is something we can accept:D